Pattern formation in layers of DNA molecules

New publication in Physical Review Letters


DNA molecules can be concentrated by electrophoretic accumulation at an interface between two immiscible polymer solutions. Apart from its relevance in applications, this process goes along with the formation of characteristic DNA concentration patterns.

Fluorescence microscopy images of patterns in the DNA concentration field at the liquid-liquid interface.

Researchers from the Technical University of Darmstadt have experimentally studied the concentration patterns and formulated a theory describing the pattern formation. The theoretical predictions based on linear stability analysis are in fair agreement with the experimental results.

S. Hardt, J. Hartmann, S. Zhao, and A. Bandopadhyay: Electric-field-induced pattern formation in layers of DNA molecules at the interface between two immiscible liquids, Physical Review Letters 124 (2020), 064501